Brilinta: Uses, Side Effects and Precautions

Brilinta is the trade name used for a drug which contains ticagrelor. Under the generic name of Ticagrelor, its trade name is Brilique and Possia in the EU. It inhibits platelet aggregation, which causes blood clotting in the blood vessels. It was approved for use in Europe in 2010 and by the US Food and Drug Administration in 2011.

What Is Brilinta Used For?

Brilinta (ticagrelor) is a drug that prevents your blood platelets from clotting (coagulating). This helps prevent unwanted formation of blood clots that can block blood vessels in the heart, brain, and other parts of the body.

Ticagrelor is often used in combination with aspirin in low doses to prevent heart attacks and strokes in people who have heart problems or those who undergo heart surgery. Aside from these common uses, Brilinta may be used for other purposes which are not listed here.

How to Use Brilinta

Brilinta Dosing

Initiate treatment by taking a loading dose of 180 mg (2 tablets of 90-mg tabs). Continue your treatment with one 90-mg tablet twice daily.

Take aspirin at 325 mg (loading dose), and use with Brilinta at a daily maintenance dose of 75 to100 mg.

What to Do If You Miss a Dose

Take your usual Brilinta dosing as soon as you remember. However, you can skip your missed dose if it is time for your next dose. Don’t take extra Brilinta to make up for your missed dose.

What to Do If You Overdose

Seek medical attention immediately or call 1-800-222-1222 (Poison Help line). Overdosing on Brilinta can lead to excessive bleeding.

Brilinta Side Effects

Common side effects of Brilinta include the following:

Consult your doctor if these side effects continue or worsen. Although most people using Brilinta do not experience serious adverse effects, some have experienced easy bruising, severe bleeding, bloody or black stools, blood in vomit or bloody urine. Tell your physician immediately if any of these occurs.

Serious allergic reactions to Brilinta are rare. However, see a doctor immediately if you experience sudden onset of rashes, itching, swelling of the face/throat/tongue, trouble breathing, and severe dizziness.

Other situations where you should call your doctor include: 

Precautions for Taking Brilinta

Do not use Brilinta if you have:

Inform your doctor if you are planning to become pregnant or may be pregnant while using Brilinta.

While using Brilinta, you must avoid:

Ask your doctor before using any medications for colds, allergy, or pain, which may contain aspirin. Check medication labels to see if they contain aspirin (often written as ASA).


Store your medications at room temperature and keep them away from heat and moisture.

To see the complete list of precautions to take, click here.  

Same Category